16th North American Regional ISSX Meeting | Baltimore, Maryland, USA
October 18 - 22, 2009

Predoctoral (Graduate Student) Category:

First Place:
Yue J. Cui, University of Kansas Medical Center, Kansas City, KS, USA
Abstract 53:  GLOBAL NUCLEAR OCCUPANCY OF PXR AND CO-EXISTENCE OF HISTONE H3K4 Di-METHYLATION RESULTING IN ACTIVATION OF DRUG-PROCESSING GENES IN MOUSE LIVER

Second Place:
Michael Gertz, University of Manchester, Manchester, United Kingdom
Abstract 58: IMPACT OF SATURATION OF CYP3A4 AND P-GLYCOPROTEIN IN VIVO ON THE PREDICTION OF INTESTINAL AVAILABILITY

Third Place:
Inna Y. Gong, University of Western Ontario, London, ON, Canada
Abstract 55: PHARMACOKINETIC AND PHARMACODYNAMIC DETERMINANTS OF WARFARIN ANTICOAGULATION RESPONSE

Postdoctoral Fellow Category:

First Place:
Ryoichi Fujiwara, University of California, San Diego, La Jolla, CA, USA
Abstract 59: EXPRESSION OF HUMAN UGT1A1 IN THE GASTROINTESTINAL TRACT OF HUMANIZED UGT1*28 MICE PLAYS AN IMPORTANT ROLE IN BILIRUBIN CLEARANCE

Second Place:
Wendy A. Teft, University of Western Ontario, London, ON, Canada
Abstract 60: ADENOVIRUS DELIVERY OF DRUG TRANSPORTERS TO GENERATE A CUSTOM POLARIZED EPITHELIAL MODEL SYSTEM

Third Place:
Kah Poh Hendrick Tan, Physiology and Experimental Biology Program, Hospital for Sick Children, Toronto, ON, Canada
Abstract 64: IDENTIFICATION OF ARYL HYDROCARBON RECEPTOR AS NOVEL TRANSCRIPTIONAL REGULATOR OF HUMAN ABCG2 (BCRP)

11th European Regional ISSX Meeting | Lisbon, Portugal
May 17-20, 2009

Predoctoral (Graduate Student) Category:

First Place
Judith Bellemare, Laval University, Quebec, Canada
Abstract #47: Functional Coexpression of UGT1 Alternative Splice Isoforms and Evidence of Protein-Protein Interaction

Second Place
Paula B.M. Luis, Universidade de Lisboa, Lisbon, Portugal
Abstract #50: Toward the Complete Elucidation of the Mitochondrial β-Oxidation Pathway of Valproic Acid and Its Interference with the Oxidation of Branched-Chain Amino Acids

Postdoctoral Fellow Category:

First Place
Laura E. Randle, The University of Liverpool, Liverpool, United Kingdom
Abstract #57: A Biochemical, Toxicological, and Proteomic Analysis Investigating the Effect of Nrf2 Gene Deletion on Paracetamol-induced Hepatoxicity In Vivo

Second Place
Michal Bitman, Charles University, Hradec Kralove, Czech Republic
Abstract #54: Effect of Valproic Acid on Extracellular Mitogen-activated Protein Kinase Pathways and Major Transcriptional Factors in Hepatoma Cell Lines and Primary Human Hepatocytes

3rd Asian Pacific Regional ISSX Meeting | Bangkok, Thailand
May 10-12, 2009

Predoctoral (Graduate Student) Category:

First Place
Laddawan Senggunprai, Tohoku University, Sendai, Japan
Abstract #52: Functional Role of ST1B Subfamily of Cytosolic Sulfotransferase to Form Natriuretic Xanthurenic Acid Sulfate

Second Place
Yuta Shibue, Tokyo University of Science, Noda, Japan
Abstract #49: Role of OATP Transporters for Hepatic Uptake and Biliary Excretion of Betalactam Antibiotics in Rats

Postdoctoral Fellow Category:

First Place
Xiang Ma, Natioanal University of Singapore, Singapore, Singapore
Abstract #56: Fluorescence-Based Screening of Pharmaceutical Reactive Metabolites Using Glutathione Immobilized 96-Well Microsomal Assay