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GURU R. VALICHERLA
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Last updated: 1/6/2020
GURU VALICHERLA
Student/Postdoc in Training Member

Professional Information
University of Pittsburgh
Postdoctoral Scholar
MAGEE-WOMENS RESEARCH INSTITUTE
204 CRAFT AVE, ROOM B535
PITTSBURGH
Pennsylvania
15213  United States
 [ Map ]
+1 4126944917 (Phone)
  Postdoctoral Scholar
  Academics
  ADME In Vitro, Animal Models, Biotransformation, Cyp Enzymes, Drug Discovery, Drug-Drug Interaction, Enzyme Induction, Enzyme Inhibition, In Vitro/In Vivo Correlation, Mass Spectrometry, Pharmacokinetics, Phase 2 Metabolism, Transporters, UGT Enzymes
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7/18/1988
Jahnavi Yaleru
Additional Information
Education/Experience
Scientific Manager - DMPK Biology, GVK Biosciences Private Limited from 2017 until 2019.
Ph.D. Scholar - Pharmacokinetics and Metabolism Division, Central Drug Research Institute (CDRI) from 2012 until 2017.
Expertise:
 Experience in in vitro ADME studies like blood plasma partitioning, plasma protein binding, in vitro CYP and UGT inhibition, CYP induction profiling using primary hepatocytes, microsomal metabolic stability, reaction phenotyping using recombinant CYPs and UGTs, permeability studies using Ussing chamber in human colorectal tissues.
 Preclinical Pharmacokinetic (PK) studies of small and large molecules (peptides): Single dose PK for bioavailability assessment, dose proportionality studies, gender differences and species comparison studies, PK parameters prediction & interpretation. PK, tissue distribution and excretion studies in rats, mice, and rabbits using oral and parenteral routes of administration.
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