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History of Xenobiotic Metabolism

(Pictured left: Society logo in use prior to 2008)

An examination of the fate of foreign compounds (xenobiotics) in biological systems is a natural outgrowth of man's curiosity about his environment and how it can affect his actions. While the majority of modern day studies concern the fate of drugs in man and animals there are extensive investigations on the fate of organic compounds in plants, animals and microorganisms. The term xenobiotic was coined to cover all organic compounds that were foreign to the organism under study. In some situations this is loosely defined to include naturally present compounds administered by alternate routes or at unnatural concentrations.

This historical look at the development of xenobiotic metabolism arose from the Year 2000 calendar project which was jointly sponsored by the International Society for the Study of Xenobiotics and Bioanalytical Systems, Inc. The Calendar was distributed to ISSX members at the Nashville meeting and via mail requests. The information contained in the calendar presentation was gathered and reviewed by the ISSX calendar editorial committee.


Editorial Committee

Dr. Patrick J. Murphy, Butler University, Indianapolis

Dr. Marcel Bickel, Universitat Bern, Switzerland
Dr. Donald Birkett, Flinders University, Australia
Dr. Bernd Clement, Universitat Kiel, Germany
Dr. Ron Estabrook, University of Texas
Dr. John Gorrod, University of Essex, UK
Dr. Jack Hinson, University of Arkansas
Dr. Peter Kissinger, Bioanalystical Systems, Inc.
Dr. Thomas Kunze, Universitat Kiel, Germany
Dr. Patrick Maurel, CNES, France
Dr. Peter Van Bladeren, TNO Nut & Food Institute Netherlands
Dr. Roland Wolf, Ninewells Hospital and Medical School, Scotland


Continue to Woehler: The Birth of Metabolism Research                                            

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