Print Page   |   Sign In   |   Join ISSX
Workshop Program


Workshop Program



Thursday, December 12, 2019

9:00 - 9:45 AM

Basic Determinants for the Disposition/ADME of Protein Therapeutics

Joseph Balthasar, SUNY Buffalo, Buffalo, NY, USA

9:45 - 10:30 AM

Clinical Examples to Showcase the Disposition Properties of Biologics

Bernd Meibohm, University of Tennessee Health Science Center, Memphis, TN, USA


10:30-10:45 AM



10:45 - 11:30 AM

Overview - Bioanalytical Methods used to Assess the Disposition of Biologics

Renuka Pillutla, BMS, Princeton, NJ, USA


11:30 - 12:15 PM

Assessing Whole-body Disposition of Biologics (Preclinical and Clinical) Using Imaging Method

Andrew Boswell, Genentech, San Francisco, CA, USA


12:15-1:30 PM

Lunch Break


1:30 - 2:15 PM

Factors Affecting Disposition of Biologics (e.g. TMDD/Immunogenicity/Physicochemical Properties)

Edit Tarcsa, AbbvieBoston, MA, USA


2:15 -3:00 PM

DDI Potential of Biologics and Disposition in Special Population

Honghui Zhou, Janssen, Spring House, PA, USA


3:00 - 3:15 PM



3:15 - 4:00 PM

Quantitative Characterization and Prediction of the Disposition of Biologics

Dhaval Shah, SUNY Buffalo, Buffalo, NY, USA


4:00 - 4:45 PM

Employing the Knowledge about the Disposition of Biologics to Support Discovery, Development, and Clinical Translation

Weirong Wang, Janssen, Springhouse, PA, USA


Friday, December 13, 2019

 9:00 - 9:30 AM

Case Study 1: Understanding the Disposition of Biologics to Treat Neurodegenerative Diseases

Drew MacCannell, BiogenBoston, MA, USA


9:30 - 10:00 AM

Case Study 2: Understanding the Disposition Vedolizumab

Maria Rosario, MA, USA


10:00 - 10:30 AM

Case Study 3: Understanding the Disposition Daratumumab

Thomas Puchalski, Janssen, Spring House, PA, USA


10:30 - 10:45 AM



10:45 - 11:15 AM

Disposition of Protein Therapeutics in Human Tissues and Tumors

Neeta Pandit, Memorial Sloan Kettering Cancer Center, New York, NY, USA


11:15 - 11:45 AM

Tissue Metabolism as a New Perspective in Discovery of Biologics

Donglu Zhang, Genentech, San Francisco, CA, USA


11:45 - 12:15 PM

Novel in vitro Techniques to Predict the Disposition of Biologics

Dan Rock, Amgen, San Francisco, CA, USA


12:15 - 1:30 PM

Lunch Break


1:30 - 2:15 PM

Quantitative Characterization of the Disposition of CAR-T

Xu Zhu, Novartis, MA, USA

2:15 - 3:00 PM

Understanding the Disposition of Oligonucleotides/SiRNA

Diane Ramsden, Alnylam, Boston, MA, USA

3:00 - 3:15 PM



3:15 - 4:00 PM

Understanding the Disposition of Gene Therapy Vectors (e.g. AAV)

Nagendra Chemuturi,  NovartisSeattle, WA, USA


4:00 - 4:45 PM

Whole-body Disposition/Tropism of AAVs in Human

Miguel Esteves, University of Massachusetts, Worcester, MA, USA 


Submit an Abstract

Association Management Software Powered by YourMembership  ::  Legal